A physician, natural historian, and professor at the University of Pennsylvania, Benjamin Smith Barton (1766-1815) was one of the central figures in Philadelphia's early national scientific establishment. Having received his medical training in European universities, Barton was appointed Professor at the University of Pennsylvania in 1789, lecturing on botany, materia medica, natural history. A prolific author, he established his reputation as one of the nation's preeminent botanists through his botanical text book The Elements of Botany (1803), but his contribtions to zoology, ethnology, and medicine were equally noteworthy. Barton's monograph on the "fascinating faculty" of the rattlesnake and his efforts in historical linguistics (New Views of the Origin of the Tribes and Nations of America, 1798) were widely read, and his Philadelphia Medical and Physical Journal (1804-1809) was one of the nation's first medical journals and an important outlet for natural historical research. The Barton Papers offer a comprehensive view of the professional work of Benjamin Smith Barton from the time of his return to the United States in 1789 until his death. The collection is divided into five series: Correspondence, Subject Files, Bound Volumes, Graphic Materials, and Printing Plates. The collection includes a particularly valuable series of botanical, medical, and natural historical drawings collected by Barton for research, reference, and publication. Among the many artists represented are William Bartram, Frederick Pursh, Pierre Turpin, and Benjamin Henry Latrobe.

Robert Cushman Murphy (1887-1973), one of the twentieth century's great ornithologists, was curator of mammals and birds at the Brooklyn Museum (1911-1917) and was curator of birds and later chairman of birds at the American Museum of Natural History (1917-1973). The world's foremost authority on sea birds, in 1936, he penned Oceanic Birds of South America, a two volume set. An ardent traveler and explorer, he kept copious notes of his travels, which he typed up, illustrated and had bound. The APS library owns forty-two bound journals. Murphy was made an APS member in 1946. A pioneer in the study of the ecology, a louse, fish, plant, lizard, an Antarctic inlet, spider, and two mountains have acquired his name. This collection contains diaries, journals, articles, addresses and observations of Murph;, generously illustrated with newspaper clippings, photographs, letters, sketches, maps, and charts.